Henderson is a town in St. Martin Parish, Louisiana, United States. The population was 1,531 at the 2000 census. It is part of the Lafayette Metropolitan Statistical Area. Bernard Apiaries Honey and Henderson Bible Church are located in Henderson.
According to the United States Census Bureau, the town has a total area of 1.7 square miles (4.4 km²), of which, 1.6 square miles (4.1 km²) of it is land and 0.1 square miles (0.26 km²) of it (2.89%) is water.